Modifications

Investigators are responsible for ongoing requirements in the conduct of approved research.  This includes obtaining prior approval from the IRB for any modifications of the previously approved research before implementing the proposed modification. 

If the investigators change the research in order to eliminate apparent immediate hazards to subjects without prior IRB approval, they should report those changes promptly to the IRB via the Safety/Other form located on the main study screen of the applicable study in eIRB+.